منابع مشابه
Fulminant meningococcemia
A 23 year old Caucasian woman was admitted to a local emergency room after awakening with “bruises” and “red spots” scattered over her body associated with fever and rigors and dizziness. Upon arrival, she had no measurable blood pressure and a temperature of 40.2 C. Petechiae and purpurae were noted primarily over her trunk and extremities. A CBC revealed WBC 2700/mm with a manual differential...
متن کاملMeningococcemia
A 31-year-old woman without history of systemic diseases presented to the emergency department with spiking fever, chills, generalized myalgia, severe epigastralgia, and watery diarrhea for 1 day. Flulike symptoms had been noted for several days. Progressive extension of petechiae skin purpura (Fig. 1) developed within 2–3 h upon arrival at the hospital. Low blood pressure persisted despite vig...
متن کاملA Case of Fulminant Meningococcemia: It Is All in the Complement
Eculizumab is a novel monoclonal antibody that inhibits complement-mediated hemolysis in patients with paroxysmal nocturnal hemoglobinuria (PNH). Complement deficiency is a well-known risk factor for meningococcal infection. We describe a case of a young patient with PNH treated with eculizumab who presented with a life-threatening case of nongroupable meningococcemia. As this new biologic agen...
متن کاملFatal meningococcemia
Within the past six years, a case of bothWaterhouse-Freidrichsen Syndrome and fulminant meningococcemia have presented to Union Memorial Hospital. Both cases presented in markedly different fashions, differed in microbiologic serogrouping, showed minimal histopathologic similarities; however achieved ultimately the same outcome through two different pathological pathways. The following case rep...
متن کاملPathogenesis of meningococcemia.
Neisseria meningitidis is responsible for two major diseases: cerebrospinal meningitis and/or septicemia. The latter can lead to a purpura fulminans, an often-fatal condition owing to the associated septic shock. These two clinical aspects of the meningococcal infection are consequences of a tight interaction of meningococci with host endothelial cells. This interaction, mediated by the type IV...
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ژورنال
عنوان ژورنال: IDCases
سال: 2017
ISSN: 2214-2509
DOI: 10.1016/j.idcr.2017.02.004